Formulation of anti-inflammatory gel from celery (apium graveolens) leaves and stalk extract tested through egg albumin denaturation assay / (Record no. 100702)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02718nam a22002657a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20261110142554.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 261110s2025 |||||||| |||| 00| 0 eng d |
| 050 ## - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | T PHAR |
| Item number | F67 2025 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Abril, John Elcid L. |
| 245 10 - TITLE STATEMENT | |
| Title | Formulation of anti-inflammatory gel from celery (apium graveolens) leaves and stalk extract tested through egg albumin denaturation assay / |
| Statement of responsibility, etc. | John Elcid L. Abril, Reign Deniela C. Batutay, Leilord M. Beltran, Athena Brittany Cates E. Comodas, and Alyssa Mae B. Navarro. |
| 264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | EAC Cavite : |
| Name of producer, publisher, distributor, manufacturer | School of Pharmacy, |
| Date of production, publication, distribution, manufacture, or copyright notice | 2025. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | xiii, 109 pages ; |
| Dimensions | 28 cm. |
| 336 ## - CONTENT TYPE | |
| Source | rdacontent |
| Content type term | text |
| 337 ## - MEDIA TYPE | |
| Source | rdamedia |
| Media type term | unmediated |
| 338 ## - CARRIER TYPE | |
| Source | rdacarrier |
| Carrier type term | volume |
| 500 ## - GENERAL NOTE | |
| General note | Experimental research |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Inflammation is a biological response to harmful stimuli that aims to eliminate pathogens or injury. This study show the effect of celery in an inflammation in the form of gel. The properties found in celery, such as flavonoids and antioxidants, have shown effectiveness in reducing inflammation associated with inflammatory conditions.<br/><br/>The toxicity of the celery's extract was assessed using the Brine Shrimp Lethality Assay, it showed a dose-dependent effect, at concentrations below 100 mcg/mL, the extract showed low toxicity, while in 50% lethality occurring at that dose, that made the selection of the concentrations that can be safely used.<br/><br/>The formulated gel was made out of carbomer as the gelling agent, glycerin and propylene glycol as humectants, distilled water as the base, triethanolamine for pH adjustment, and methylparaben as the preservative. The gel's physical properties were within acceptable ranges: the pH 7.68±0.038), viscosity (50,414.67±12.66 cP), and turbidity (31.67±23.18 NTU), it shows an ensuring stability and compatibility for topical use.<br/><br/>The anti-inflammatory activity was evaluated through the Egg Albumin Denaturation Assay. It showed a dose-dependent inhibition of the protein denaturation of the forumlated gel. The four extract concentrations achieved 62.66% (25%), 78.96% (50%), 96.14% (75%), and 95.74% (100%) inhibition. The 75% concentration yielded the highest and most consistent anti-inflammatory effect. Thus, the statistical analysis validated the significance of these results, suggesting that the formulated gel may serve as an effective alternative to standard anti-inflammatory drugs. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Relator code | author |
| Personal name | Batutay, Reign Deniela C. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Relator code | author |
| Personal name | Beltran, Leilord M. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Relator code | author |
| Personal name | Comodas, Athena Brittany Cates E. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Relator code | author |
| Personal name | Navarro, Alyssa Mae B. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Library of Congress Classification |
| Koha item type | THESIS |
| Call number prefix | EAC Cavite-Thesis Section |
| Suppress in OPAC | No |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Shelving location | Date acquired | Total Checkouts | Full call number | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Library of Congress Classification | EAC Library Cavite | EAC Library Cavite | EAC Cavite-Thesis Section | 11/10/2026 | T PHAR F67 2025 | ML-TH2823 | 11/10/2026 | 11/10/2026 | THESIS |