02434nam a22002417a 4500003000400000005001700004008004100021050002100062100002000083245022300103264004500326300002800371336002100399337002500420338002300445500002600468504004000494520153500534700003202069700003702101700002902138700002502167OSt20261104144253.0261104s2025    |||||||| |||| 00| 0 eng d  aT PHARbF67 20251 aBanting, Eunice10aFormulation of liquid dosage form with the isolated citric acid from suha (citrus maxima) :bbasis for stability studies /cEunice Banting, Sofia Julia Cortez, Chrislyn Ann Joy Gloton, Richbern Sayson, and Adelyne Tud.  aEAC Cavite :bSchool of Pharmacy,c2025.  avii, 95 pages ;c28 cm.  2rdacontentatext  2rdamediaaunmediated  2rdacarrieravolume  aExperimental research  aIncludes bibliographical references  aCitrus maxima is known to contain different bioactive chemical constituents, among which is citric acid, used in the pharmaceutical industry and recognized for its antioxidant qualities. The citric acid present in the Citrus maxima has limited research in regard to the incorporation of the citric acid in a liquid dosage form. The purpose of the study is to formulate a physically stable liquid dosage form with the use of citric acid isolated from the fruit Citrus maxima. The juice from the pulp of the fruit, from which the citric acid was isolated, reveals a 19.76% yield of citric acid. The suha juice was diluted (distilled water) and neutralized (NaOH) with a 7.00 to 7.20 pH level. The sample underwent various heating processes to crystallize. FTIR analysis indicated the presence of citric acid, and impurity tests showed moisture content (32.71% to 37.70%). Concentration from titration of citric acid (0.031 to 0.040 M). The stability of the liquid dosage form incorporated with the isolated citric acid revealed an acidic pH, stable temperature, and physical properties. The thin chromatography analysis using solvent (distilled water, acetic acid, and butanol) for the detection of citric acid and identification of RF value (0.95 to 0.98), revealing the presence of citric acid. The pH (4.05-4.18) of the formulation at various temperatures for one month shows its stability over an extended period. In conclusion, the citric acid isolated from the Citrus maxima fruit helps stabilize the formulated liquid dosage.1 4authoraCortez, Sofia Julia1 4authoraGloton, Chrislyn Ann Joy1 4authoraSayson, Richbern1 4authoraTud, Adelyne